Non-Coding Genome
– Lukáš Trantírek
From fragments to high affinity binders interfacing integrated structural biology, medicinal chemistry and artificial intelligence
,
Evropská unie, 2023 - 2026
Structure, biology and medical potential of blood plasma-derived ultra-short cell-free DNA
,
Grantová agentura ČR, 2022 - 2025
In vitro and In-cell characterization of Quadruplex-duplex hybrids: conformation, folding, ligand binding and implications for in-cell NMR based assays
,
Evropská unie, 2022 - 2024
STRUCTURAL BIOLOGY – NEXT GENERATION: from isolated molecules to cells, from cells to tissues.
,
Grantová agentura ČR, 2019 - 2023
Atomically resolved in vivo NMR spectroscopy as a novel tool for biological testing of therapeutically important genomic non-canonical DNA targets and their interactions with drugs in phenotypically diversified cancer cells.
,
Ministry of Health of the CR, 2019 - 2022
Enabling user access to bioreactors for real-time in-cell NMR
,
Instruct Academic Service Limited, 2019 - 2021
Studium interakcí DNA-ligand pomocí in-cell NMR spektroskopie
,
Ministerstvo školství, mládeže a tělovýchovy ČR, 2018 - 2019
Polymorfní G-quadruplexy v promotorových oblastech genů
(GA17-12075S),
Grantová agentura ČR, 2017 - 2019
Profiling DNA structure and DNA ligand interactions inside nuclei of live mammalian cells by in-cell NMR spectroscopy.
,
Masarykova univerzita, 2018 - 2019
Charakterizace struktury nukleových kyselin v komplexním prostředí živých buněk pomocí vysoce rozlišené NMR spektroskopie
(GA16-10504S),
Grantová agentura ČR, 2016 - 2018
Towards selective targeting of DNA G-quadruplexes by small molecular weight ligands within the human genome
(4SGA8580),
Jihomoravský kraj, 2014 - 2017
