DIANA panel for testing of selectivity of inhibitors of clinically relevant protein kinases and its application in the drug discovery market. Preclinical development of new inhibitors of CDK11 - key enzyme for growth of cancer cells.
,
, 2021 - 2024
Characterization of kinase activity of cyclin-dependent kinase 11 (CDK11), an essential enzyme for the growth of cancer
,
Grantová agentura ČR, 2021 - 2023
CDK12 controls G1/S progression by regulating RNAPII processivity at core DNA replication genes
,
Masarykova univerzita, 2019 - 2020
Characterization of novel substrates and function for ovarian cancer-related cyclin-dependent kinase 12 (Cdk12)
(GA17-13692S),
Grantová agentura ČR, 2017 - 2019
Charakterization of a new factor in regulation of transcription/mRNA processing of histone genes
,
Masarykova univerzita, 2018 - 2019
Regulace genové exprese novým faktorem vázajícím mRNA
(GA16-10930S),
Grantová agentura ČR, 2016 - 2018
Genome-wide analyses of a “non-canonical” cyclin-dependent kinase (CDK)
(MUNI/E/0080/2017),
Masarykova univerzita, 2017 - 2017
Role Cdk12 a C-terminální domény RNA polymerázy II v transkripcně regulovaném procesu genomové nestability
(GA14-09979S),
Grantová agentura ČR, 2014 - 2016
Funkční charakterizace unikátních zásobních ribonukleoproteinových částic v pylu
(GAP501/11/1462),
Grantová agentura ČR, 2011 - 2014
The roles of Cdk12 in ovarian tumorigenesis
(MFR2013),
Foundations - International - Marsha Rivkin Center, 2013 - 2014
The roles of Cdk12 in ovarian tumorigenesis
,
Ostatní - zahraniční, 2013 - 2014
Nová izoforma cyklinu K je partnerem kinázy cdk12 regulující transkripci a alternativní sestřih u eukaryot
(GAP305/11/1564),
Grantová agentura ČR, 2011 - 2013
Novel methylation of Hexim1 and cyclin composition of positive trancription elongation factor b (P-TEFb) regulate kinase activity of cdk9
(ME09047),
MEYS - KONTAKT, 2009 - 2013
Regulation and function of P-TEFb complexes
(SRGA 454),
South Moravian Region - SoMoPro, 2010 - 2013
Regulace a funkce P-TEFb komplexů
,
Jihomoravský kraj, 2010 - 2013
