Identification of enzymes oxidizing the tyrosine kinase inhibitor cabozantinib: Cabozantinib is predominantly oxidized by CYP3A4 and its oxidation is stimulated by cyt b5 activity
BIOMEDICINES
INDRA, R.; VAVROVÁ, K.; POMPACH, P.; HEGER, Z.; HODEK, P., 2020: Identification of enzymes oxidizing the tyrosine kinase inhibitor cabozantinib: Cabozantinib is predominantly oxidized by CYP3A4 and its oxidation is stimulated by cyt b5 activity. BIOMEDICINES , p. 1 - 14, doi: 10.3390/biomedicines8120547; FULL TEXT