About event
This presentation explores pangenome variant calling, focusing on the fundamental concepts and practical applications in genomic analysis. It covers the construction and understanding of pangenome graphs, which represent multiple genomic sequences and their variations through interconnected nodes and paths. The discussion encompasses key tools like PGGB and ODGI for building and manipulating these graphs, as well as methods for graph decomposition. The presentation also addresses visualization techniques, particularly the representation of divergent regions through bubble structures, and explains how various types of genetic variations are captured and analyzed within the pangenome framework.
The lecture is part of the Bioinformatics Seminar Series, which aims to invite exciting speakers working on the current state-of-the-art bioinformatics problems.