About event
Abstract
Micromotors represent one of the most exciting horizons in micro and nanotechnologies. The utilization of self-propelled micromotors in (bio)chemical assays has led to a fundamentally new approach where their continuous movement around the sample and the mixing associated effect, all this as a collective behavior, greatly enhances the target-receptor interactions and hence the performance of the bioassay [1-3]. We are focusing on the design and development of micromotors which are constituted by (nanostructured) layers (tubular-based shape) and particles (Janus-based shape) that confer them self-propulsion using (photo)-catalytic propulsion and magnetic guidance with biocompatibility. They also smartly incorporate nanomaterials and molecular recognition-based functionalization to obtain sensitivity and exquisite selectivity on board using electrochemical and fluorescence detection approaches. We humbly found that micromotor technology is an attractive alternative to performing fast, reliable bioassays and diagnostic testing at the micro and nanoscale [4-6]. This seminar will discuss the potential of (photo)-catalytic magnetic micromotors as a dynamic collective biosensing approach for disruptive diagnosis, drawing some future directions in the nanomedicine field.
References
[1] J. Wang, Biosen. Bioelectron. 76 (2016) 234.
[2] J. Parmar, D. Vilela, K. Villa, J. Wang, S. Sánchez, J. Am. Chem. Soc. 240 (2018) 9317
[3]M. Pacheco, M.A. López, B. Jurado-Sánchez, A. Escarpa, Anal. Bioanal. Chem. 411 (2019) 6561
[4] K. Yuan, M. Pacheco, B. Jurado, A. Escarpa. Adv. Intell. Syst. 3 (2021) 2100002
[5]R. Maria Hormigos, B. Jurado-Sánchez, A. Escarpa. Anal. Bioanal. Chem. 414 (2022) 7035.
[6] J. Bujalance-Fernández, B. Jurado-Sánchez, A. Escarpa. Chem. Comm. 59 (2023), 10464
ACKNOWLEDGMENTS
The financial support of grant of the Community of Madrid, grant number Y2020/NMT6312 (NEURO-CHIP-CM) are gratefully acknowledged.
