Profile
Bio
Marek Mráz conducts research on the biology of chronic lymphocytic leukaemia (the most common leukaemia in adults) and other malignancies originating from B-lymphocytes. He studies how these cancer cells interact with other immune cells and how signals from the B-cell receptor (BCR) influence their behaviour. He has described new mechanisms of this cellular communication and is also exploring novel inhibitors and therapy combinations that could improve the treatment of leukaemia and other blood cancers.
He was trained in both clinical medicine and molecular biology and subsequently conducted postdoctoral research in the United States at the University of California, San Diego, and Mayo Clinic. He received a grant from the European Hematology Association (2015), prestigious ERC Starting Grant from the European Research Council (2019), and in 2024 the most prestigious national grant (GACR EXPRO). He collaborates closely with hematologists at University Hospital Brno and with many international teams.